For Care Providers


Comprehensive 24-Hour Urinary Steroid Hormone Profile


At Meridian Valley Lab (MVL), urinary steroid hormones are precisely quantified via gas chromatography, mass spectrometry and proprietary laboratory procedures tied to exacting laboratory quality standards. For nearly three decades, MVL continues to offer the finest laboratory testing services. MVL is certified by the State of Washington.

Our New ComprehensivePLUS Hormone Profile includes these recently added analytes:

  • Classic Comprehensive plus 2-Hydroxyestrogens, 16α-Hydroxyestrone, 2-Methoxyestrone, 2-Methoxyestradiol, 5α-Androstanediol, 5ß-Androstanediol, 11ß-Hydroxyandrosterone, 11ß-Hydroxyetiocholanolone

Still Available is our Classis Comprehensive Hormone Profile testing all the analytes in our Sex and Adrenal Hormone Profiles.

Adrenal Steroids Profile Analytes:

  • DHEA, Cortisone, Cortisol, Pregnenolone, Aldosterone, Etiocholanolone, Adrosterone, Creatinine, Pregnanetriol, Tetrahydrocortisone, Tetrahydrocortisol, Allo-Tetrahydrocortisol, Tetrahydrocorticosterone, Allo-Tetrahydrocorticosterone

Sex Hormone Profile Analytes:

  • DHEA, Estrone, Estradiol, Estriol, Pregnenediol, Testosterone, Etiocholanolone, Androsterone, Creatinine, Pregnanetriol

Clinical Applications Of Urinary Hormone Profiles

Cortisol and Cortisone
  • Addison's disease
  • Adrenal fatigue (pre and post ACTH)
  • Synthetic corticosteroid toxicity
  • Altered expression of 11-ß-hydroxy steroid dehydrogenases
  • Hypertension (salt-sensitive)
  • Apparent mineralocorticoid excess
  • Emotional stress
  • Bio-Identical hormone replacement
  • Cushing's syndrome

Estrogens and Pregnanediol
  • Perimenopause
  • Menopause
  • Bio-Identical hormone replacement
  • Liver detoxification
  • Estrogen "dominance"

Androgens
  • Andropause
  • Decreased libido
  • Bio-Identical hormone replacement

24-hour urinary steroid hormone profiles are widely used in clinical diagnostics. Recent developments of natural hormone replacement therapies, available OTC (pregenolone, DHEA, progesterone) and by prescription (Triple Estrogen, estriol, testosterone) have led to new applications for steroid hormone testing. Many clinicians served by MVL use urinary hormone profiles as an integral part of natural hormone replacement therapy, including diagnosis, dosage adjustment and monitoring.

"I prefer to use the 24-hour urine test, because nearly all hormones are secreted in 'bursts' and 'pulses' and a single blood draw or saliva collection (or even two or three of them) may not provide a representative sample."
Natural Hormone Replacement
by Jonathan V. Wright M.D. and John Morgenthaler
Aldosterone
  • Mineralocorticoid excess
Hormone
Cortisol
Indications
  • Monitoring bio-identical hormone replacement
  • Adrenal insufficiency (tested before and after ACTH administration)
  • Breast lesions
  • Anorexia nervosa
  • Hypertension
  • Emotional stress
  • Idiopathic hirsutism
  • Carcinoma
  • Endocrine disorders
  • Chronic fatigue syndrome
  • Fibromyalgia
  • Rheumatoid arthritis
  • 5-alpha reductase deficiency
  • Monitoring liver detoxification


Read more detailed information     24-Hour Comprehensive Steroid Hormone Profile Interpretation


ADDITIONAL INFORMATION
Pre/Post Adrenal Stimulation Adrenal Thyroid Panel Serum DHEA
Methods for the Determination of Steroid Hormones