Code: 4080
PLUS Hormone Profile
A comprehensive 24-hour urine hormone panel for rhythm, metabolism,
and BHRT monitoring.
- At-home collection
- 24-hour coverage
- BHRT friendly
- Clinician-ready report
Full marker list by category
Estrogens (7)
Estrone, Estradiol, 2-Hydroxyestrone…
- Estrone (E1)
- Estradiol (E2)
- Estriol (E3)
- 2-Hydroxyestrone
- 16α-Hydroxyestrone
- 2-Methoxyestrone
- 2-Methoxyestradiol
Progesterone (1)
Pregnanediol
- Pregnanediol
Androgens (6)
DHEA, Testosterone, Androsterone…
- DHEA
- Testosterone
- 5α-Androstanediol
- 5β-Androstanediol
- Androsterone
- Etiocholanolone
Glucocorticoids (8)
Cortisol, Cortisone, THF / Allo-THF…
- Pregnanetriol
- Cortisone
- Cortisol
- Tetrahydrocortisone (THE)
- Allo-Tetrahydrocortisol (Allo-THF)
- Tetrahydrocortisol (THF)
- 11β-Hydroxyandrosterone
- 11β-Hydroxyetiocholanolone
Mineralocorticoids (4)
Aldosterone, THB / Allo-THB…
- Aldosterone
- Allo-Tetrahydrocorticosterone (Allo-THB)
- Tetrahydrocorticosterone (THB)
- 11-Dehydrotetrahydrocorticosterone (11-DHTB)
Electrolytes / Na:K Ratio
(3)
Sodium, Potassium, Ratio
(3)
- Sodium (Na⁺)
- Potassium (K⁺)
- Sodium/Potassium Ratio (Na:K)
Thyroid (2)
Free T3, Free T4
- Free T3
- Free T4
Organic Acids (2)
Kynurenic, Xanthurenic
- Kynurenic Acid
- Xanthurenic Acid
View CPT Codes
82160
82533
82670
82677
82679
82542
82570
82626
82696
84135
84138
84403
84439
84481
84300
84133
81050
83921 × 2
84999, 81050.
What’s Measured in the PLUS Panel?
The PLUS profile measures core sex steroids and adrenal hormones with
key metabolites and enzyme activity, including:
-
Estrogens (E1, E2, E3) and
estrogen metabolites - Pregnanediol (a marker of progesterone activity)
-
DHEA, testosterone, and their
metabolites -
Cortisol, cortisone, and
glucocorticoid metabolites - Mineralocorticoids (aldosterone and metabolites)
- Free T3 and T4 for thyroid hormone evaluation
- Electrolytes (Sodium, Potassium, and Na:K ratio)
- Organic acids (Kynurenic acid, Xanthurenic acid)
Why Choose This Test?
The PLUS panel is ideal when a broad hormone overview is needed for:
- Fatigue, insomnia, or anxiety
- Perimenopausal or menopausal transitions
- Suspected estrogen dominance or adrenal dysregulation
- Thyroid symptoms that don’t show in serum labs
- Monitoring lifestyle or BHRT adjustments
Because it captures a full 24-hour period, the PLUS
profile can reveal rhythm patterns and enzyme activity that spot checks
may miss.
Easy at-Home Collection
- Receive kit with jug, clear instructions, and return supplies
- Collect urine over a full 24-hour period
- Return to MVL for analysis and a detailed, clinician-ready report
Related Testing Options
ULTIMATE Hormone Profile
Our most complete 24-hour urine hormone panel with expanded markers.
Sex Hormone Profile
Focused assessment of estrogens, progesterone markers, and androgens.
